SCHEMBL7209847

SCHEMBL7209847

COCCOc1nc(N)c2nc(Br)n(Cc3ccccc3F)c2n1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.55
NUDT1 P36639 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19539681 0.88 TLR7 (0.66) TLR7
SCHEMBL509587 0.85 TLR7 (0.74) TLR7NUDT1
SCHEMBL12305227 0.84 TLR7 (0.51) TLR7NUDT1
SCHEMBL7205658 0.83 TLR7 (0.60) TLR7NUDT1
SCHEMBL16481784 0.80 TLR7 (0.61) TLR7NUDT1
SCHEMBL17154083 0.80 TLR7 (0.61) TLR7NUDT1
SCHEMBL12305230 0.80 TLR7 (0.59) TLR7
SCHEMBL12305231 0.79 TLR7 (0.52) TLR7NUDT1
SCHEMBL2058718 0.78 TLR7 (0.59) TLR7NUDT1
SCHEMBL12726966 0.78 TLR7 (0.47) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1035123-B1 NOVEL HETEROCYCLIC COMPOUNDS SUMITOMO PHARMA (JP) 2003-08-20 EP disclosed
US-6329381-B1 INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2001-12-11 US disclosed
EP-1035123-A1 NOVEL HETEROCYCLIC COMPOUNDS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2000-09-13 EP disclosed