Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.64 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.64 |
| ▸ | THPO | P40225 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357638 | 0.87 | ANPEP (0.54) | PTGS1PTGS2MAPTALDH1A1CXCR1 | |
| SCHEMBL11138504 | 0.85 | PTGS1 (0.66) | PTGS1PTGS2MAPTALDH1A1CXCR1 | |
| SCHEMBL14201846 | 0.85 | PTGS1 (0.66) | PTGS1PTGS2MAPTALDH1A1CXCR1 | |
| SCHEMBL11850012 | 0.84 | PTGS1 (0.60) | PTGS1PTGS2MAPTALDH1A1CXCR1 | |
| SCHEMBL11850747 | 0.83 | PTGS1 (0.59) | PTGS1PTGS2MAPTALDH1A1CXCR1 | |
| SCHEMBL27536953 | 0.81 | PTGS1 (0.60) | PTGS1PTGS2MAPTALDH1A1CXCR1 | |
| SCHEMBL16091082 | 0.81 | PTGS1 (0.60) | PTGS1PTGS2MAPTALDH1A1CXCR1 | |
| SCHEMBL764365 | 0.81 | MAPT (0.74) | PTGS1PTGS2MAPTALDH1A1CXCR1 | |
| SCHEMBL237090 | 0.80 | FFAR1 (0.70) | MAPTALDH1A1CYP3A4HPGDFFAR1 | |
| SCHEMBL1149768 | 0.80 | FFAR1 (0.70) | MAPTALDH1A1CYP3A4HPGDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610875-B1 | Forming bidentate ligands ofr assymetric catalysts; bromina-ting diaryldiol; esterifying with sulfonic acid; substituting cyano for bromine groups; coupling with a dicyclophosphine | RHODIA CHIMIE (FR) | 2003-08-26 | — | — | US | disclosed |