Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516033 | 0.86 | TAAR1 (0.73) | TAAR1SLC6A2CYP2D6LMNASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL2477835 | 0.84 | SLC6A2 (0.70) | TAAR1SLC6A2CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL11782901 | 0.80 | SLC6A2 (0.64) | TAAR1SLC6A2CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL4676258 | 0.80 | TAAR1 (0.64) | TAAR1SLC6A2CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL24228162 | 0.78 | SLC6A2 (0.61) | TAAR1SLC6A2CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL20821495 | 0.78 | SLC6A2 (0.61) | TAAR1SLC6A2CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL2024074 | 0.78 | SLC6A2 (0.61) | TAAR1SLC6A2CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL2024077 | 0.78 | SLC6A2 (0.61) | TAAR1SLC6A2CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL7957804 | 0.78 | SLC6A2 (0.61) | TAAR1SLC6A2CYP2D6LMNASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL4091907 | 0.78 | SLC6A2 (0.61) | TAAR1SLC6A2CYP2D6LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314731-A2 | Substituted pyrimidine compounds and their use | AMGEN INC. (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-1314732-A2 | Substituted pyrimidine compounds and their use | AMGEN INC. (US) | 2003-05-28 | — | — | EP | disclosed |