2-Chloropyridine

2-Chloropyridine

SCHEMBL7210246

Clc1ccccn1.c1ccncc1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.80
NAPRT Q6XQN6 2/20 0.45
TSHR P16473 1/20 0.45
CYP2A6 P11509 2/20 0.42
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
LMNA P02545 2/20 0.42
P4HTM Q9NXG6 2/20 0.42
KDM4E B2RXH2 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
METAP1 P53582 1/20 0.42
BLM P54132 1/20 0.42
HIF1A Q16665 1/20 0.42
DOHH Q9BU89 1/20 0.42
TRPA1 O75762 1/20 0.41
NOTUM Q6P988 1/20 0.40
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Chloropyridine SCHEMBL27916959 0.98 TDP1 (0.76) TDP1NAPRTTSHRCYP2A6CCR1
2-Chloropyridine SCHEMBL11817165 0.98 TDP1 (0.76) TDP1NAPRTTSHRCYP2A6CCR1
2-Chloropyridine SCHEMBL28267674 0.92 TDP1 (0.84) TDP1CYP2A6CCR1CCR5CCR8
2-Chloropyridine SCHEMBL11389784 0.89
2-Chloropyridine SCHEMBL16637 0.89
2-Chloropyridine SCHEMBL10690176 0.89 TDP1 (1.00) TDP1CCR1CCR5CCR8LMNA
2-Chloropyridine SCHEMBL28283275 0.89 TDP1 (1.00) TDP1CCR1CCR5CCR8LMNA
2-Chloropyridine SCHEMBL29402311 0.89
2-Chloropyridine SCHEMBL932532 0.87
2-Chloropyridine SCHEMBL8545796 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677787-B Cobalt pyrithione complex, preparation method and application thereof 云南师范大学 2024-04-26 CN claimed
EP-1184375-B1 PROCESS FOR PREPARING TRIBROMOMETHYLSULFONYLPYRIDINE SUMITOMO SEIKA CHEMICALS (JP) 2003-10-29 EP claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
CN-115677787-B Cobalt pyrithione complex, preparation method and application thereof 云南师范大学 2024-04-26 CN disclosed
CN-115677787-A Mercapto pyridine cobalt complex and preparation method and application thereof 云南师范大学 2023-02-03 CN disclosed
CN-102414197-B insecticidal pyridine compounds DOW AGROSCIENCES LLC (US) 2015-11-25 CN disclosed
WO-2015042405-A1 PH SWITCHABLE REAGENTS AND METHODS FOR THEIR USE IMPOSSIBLE FOODS INC. (US) 2015-03-26 WO disclosed
CN-102480964-A Pyranyl aryl methyl benzoquinazolinone M1 receptor positive allosteric modulators MERCK SHARP & DOHME 2012-05-30 CN disclosed
CN-102414197-A Insecticidal pyridine compounds DOW AGROSCIENCES LLC 2012-04-11 CN disclosed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO disclosed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO disclosed
US-4278745-A IODINE, 2 PYRIDINE-BASED COMPOUNDS MEDTRONIC, INC. (US) 1981-07-14 US disclosed