Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764947 | 0.95 | KCNH2 (0.54) | KCNH2MC4R | |
| SCHEMBL4540650 | 0.88 | KCNH2 (0.59) | KCNH2MC4R | |
| SCHEMBL7210955 | 0.88 | KCNH2 (0.59) | KCNH2MC4R | |
| SCHEMBL4365701 | 0.86 | KCNH2 (0.63) | KCNH2MC4R | |
| SCHEMBL5766700 | 0.85 | KCNH2 (0.58) | KCNH2MC4R | |
| SCHEMBL4006989 | 0.84 | MC4R (0.62) | KCNH2MC4R | |
| SCHEMBL4813922 | 0.84 | KCNH2 (0.58) | KCNH2MC4R | |
| SCHEMBL14027066 | 0.84 | KCNH2 (0.54) | KCNH2MC4R | |
| SCHEMBL4364624 | 0.84 | KCNH2 (0.60) | KCNH2MC4R | |
| SCHEMBL14046095 | 0.84 | KCNH2 (0.60) | KCNH2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363890-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002062766-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-08-15 | — | — | WO | claimed |
| EP-1363890-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002062766-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-08-15 | — | — | WO | disclosed |