SCHEMBL7211538

SCHEMBL7211538

COCCOc1nc(N)c2nc(OC)n(Cc3ccc(F)cc3)c2n1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.60
NUDT1 P36639 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21449093 0.90 TLR7 (0.61) TLR7NUDT1
SCHEMBL4128956 0.90 TLR7 (0.61) TLR7NUDT1
SCHEMBL4134546 0.89 TLR7 (0.60) TLR7NUDT1
SCHEMBL12726879 0.89 TLR7 (0.60) TLR7NUDT1
SCHEMBL510344 0.89 TLR7 (0.74) TLR7NUDT1
SCHEMBL22533653 0.88 TLR7 (0.61) TLR7NUDT1
SCHEMBL4139813 0.87 TLR7 (0.60) TLR7NUDT1
SCHEMBL7205658 0.87 TLR7 (0.60) TLR7NUDT1
SCHEMBL7210390 0.87 TLR7 (0.60) TLR7NUDT1
SCHEMBL4136059 0.86 TLR7 (0.57) TLR7NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1035123-B1 NOVEL HETEROCYCLIC COMPOUNDS SUMITOMO PHARMA (JP) 2003-08-20 EP disclosed
US-6329381-B1 INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2001-12-11 US disclosed
EP-1035123-A1 NOVEL HETEROCYCLIC COMPOUNDS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2000-09-13 EP disclosed