Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 4/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15131203 | 0.89 | CASR (0.50) | CASRSLC6A2SLC6A4ADRA2CHTR2C | |
| SCHEMBL13077646 | 0.88 | CASR (0.60) | CASRSLC6A2SLC6A4ADRA2CHTR2C | |
| SCHEMBL15131229 | 0.85 | POLB (0.61) | CASRSLC6A2SLC6A4ADRA2CHTR2C | |
| SCHEMBL5193705 | 0.85 | POLB (0.61) | CASRSLC6A2SLC6A4ADRA2CHTR2C | |
| SCHEMBL2341650 | 0.85 | POLB (0.61) | CASRSLC6A2SLC6A4ADRA2CHTR2C | |
| SCHEMBL3509608 | 0.85 | ACP3 (0.48) | CASRSLC6A2SLC6A4ADRA2CHTR2C | |
| SCHEMBL15131155 | 0.84 | CASR (0.56) | CASRSLC6A2SLC6A4ADRA2CHTR2C | |
| Hydrochloric Acid SCHEMBL3067899 | 0.84 | CASR (0.60) | CASRSLC6A2SLC6A4ADRA2CHTR2C | |
| Hydrochloric Acid SCHEMBL3082165 | 0.84 | CASR (0.60) | CASRSLC6A2SLC6A4ADRA2CHTR2C | |
| Hydrochloric Acid SCHEMBL607723 | 0.84 | CASR (0.60) | CASRSLC6A2SLC6A4ADRA2CHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907631-B1 | INORGANIC ION RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMA INC (US) | 2003-06-18 | — | — | EP | disclosed |