SCHEMBL7211804

SCHEMBL7211804

NCC(O)C(O)[C@H](N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.58
SLCO1B1 Q9Y6L6 1/20 0.58
SLC7A5 Q01650 1/20 0.40
GABRR1 P24046 2/20 0.37
LMNA P02545 1/20 0.37
SLC1A3 P43003 7/20 0.34
SLC1A2 P43004 7/20 0.34
SLC1A1 P43005 7/20 0.34
PDE4A P27815 1/20 0.34
GSR P00390 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC7A11 Q9UPY5 1/20 0.33
RNPEP Q9H4A4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7211805 1.00 USP2 (0.58) USP2SLCO1B1SLC7A5GABRR1LMNA
SCHEMBL6431831 1.00 USP2 (0.58) USP2SLCO1B1SLC7A5GABRR1LMNA
SCHEMBL17054062 0.84
SCHEMBL31074088 0.84 USP2 (0.50) USP2SLCO1B1SLC7A5GABRR1LMNA
SCHEMBL17047028 0.84
SCHEMBL23120067 0.84
SCHEMBL9060368 0.84
SCHEMBL14830311 0.81 USP2 (0.54) USP2SLCO1B1SLC7A5GABRR1SLC1A3
SCHEMBL16731973 0.81 USP2 (0.54) USP2SLCO1B1SLC7A5GABRR1SLC1A3
SCHEMBL1854670 0.81 USP2 (0.54) USP2SLCO1B1SLC7A5GABRR1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2760881-B1 NOVEL PEPTIDE DERIVATIVES AS ANTIBIOTICS NOSOPHARM (FR) 2017-11-01 EP claimed
US-9260481-B2 Peptide derivatives as antibiotics NOSOPHARM (FR) 2016-02-16 US claimed
US-20150175659-A1 Peptide Derivatives as Antibiotics INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2015-06-25 US claimed
EP-2760881-A1 NOVEL PEPTIDE DERIVATIVES AS ANTIBIOTICS Nosopharm (FR) 2014-08-06 EP claimed
WO-2013045600-A1 NOVEL PEPTIDE DERIVATIVES AS ANTIBIOTICS NOSOPHARM (FR) 2013-04-04 WO claimed
EP-2760881-B1 NOVEL PEPTIDE DERIVATIVES AS ANTIBIOTICS NOSOPHARM (FR) 2017-11-01 EP disclosed
US-9260481-B2 Peptide derivatives as antibiotics NOSOPHARM (FR) 2016-02-16 US disclosed
US-20150175659-A1 Peptide Derivatives as Antibiotics INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2015-06-25 US disclosed
EP-2760881-A1 NOVEL PEPTIDE DERIVATIVES AS ANTIBIOTICS Nosopharm (FR) 2014-08-06 EP disclosed
WO-2013045600-A1 NOVEL PEPTIDE DERIVATIVES AS ANTIBIOTICS NOSOPHARM (FR) 2013-04-04 WO disclosed
US-6613738-B1 Comprising 1,2-dihydroxy-homotyrosine, 4-hydroxyproline, threonine, glutamine, 3-,4-dihydroxymethylproline, 4,5-dihydroxyornithine and lipid HMV CORPORATION 2003-09-02 US disclosed
WO-2000009735-A1 A CYCLIC LIPOPEPTIDE FROM CRYPTOSPORIOPSIS QUERCINA POSSESSING ANTIFUNGAL ACTIVITY STROBEL GARY A (US) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150175659-A1 Peptide Derivatives as Antibiotics VIP, NGLY1, NRDC USP2 2008/4885SLCO1B1 2441/4885SLC7A5 610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.