⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14076877 | 0.83 | — | — | |
| SCHEMBL4482466 | 0.81 | — | — | |
| SCHEMBL2415617 | 0.76 | — | — | |
| SCHEMBL12669525 | 0.76 | — | — | |
| SCHEMBL10437243 | 0.76 | — | — | |
| SCHEMBL9338826 | 0.74 | — | — | |
| SCHEMBL20432 | 0.74 | — | — | |
| SCHEMBL5621999 | 0.74 | — | — | |
| SCHEMBL10580480 | 0.73 | — | — | |
| SCHEMBL15070042 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000889-B1 | 3\"-N-DEMETHYL-3\"-N-SUBSTITUTED-4,6-DI-0-(AMINOGLYCOSYL)-1,3-DIAMINOCYCLITOLS, METHODS FOR THEIR PREPARATION AND THEIR APPLICATION AS ANTIBIOTICS | BAYER AG (DE) | 1981-04-29 | — | — | EP | claimed |
| EP-2751084-B1 | PYRIMIDINE CARBOXAMIDE DERIVATIVES | EUDIS BIOTECH LLC (CN) | 2016-09-21 | — | — | EP | disclosed |
| US-9249107-B2 | Pyrimidine carboxamide derivatives | MAEHR HUBERT (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150087665-A1 | Pyrimidine carboxamide derivatives | Maehr, Hubert (US) | 2015-03-26 | — | — | US | disclosed |
| EP-2834223-A2 | (1,2,3-TRIAZOLYL) SULFONYL DERIVATIVES | Apac Pharmaceutical LLC. (US) | 2015-02-11 | — | — | EP | disclosed |
| US-8853248-B2 | (1,2,3-triazolyl)sulfonyl derivatives | MAEHR HUBERT (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2751084-A1 | PYRIMIDINE CARBOXAMIDE DERIVATIVES | Apac Pharmaceutical LLC. (US) | 2014-07-09 | — | — | EP | disclosed |
| US-8580805-B2 | Pyrimidine carboxamide derivatives | MAEHR HUBERT (US) | 2013-11-12 | — | — | US | disclosed |
| US-20130267568-A1 | (1,2,3-Triazolyl)sulfonyl Derivatives | MAEHR HUBERT (US) | 2013-10-10 | — | — | US | disclosed |
| WO-2013151597-A2 | (1,2,3-TRIAZOLYL) SULFONYL DERIVATIVES | APAC PHARMACEUTICAL LLC. (US) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013032522-A1 | PYRIMIDINE CARBOXAMIDE DERIVATIVES | APAC PHARMACEUTICAL LLC. (US) | 2013-03-07 | — | — | WO | disclosed |
| US-20120053346-A1 | Pyrimidine Carboxamide Derivatives | MAEHR HUBERT (US) | 2012-03-01 | — | — | US | disclosed |
| EP-0000889-B1 | 3\"-N-DEMETHYL-3\"-N-SUBSTITUTED-4,6-DI-0-(AMINOGLYCOSYL)-1,3-DIAMINOCYCLITOLS, METHODS FOR THEIR PREPARATION AND THEIR APPLICATION AS ANTIBIOTICS | BAYER AG (DE) | 1981-04-29 | — | — | EP | disclosed |
| US-4224315-A | Pseudotrisaccharides and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-23 | — | — | US | disclosed |
| EP-0000889-A1 | 3\"-N-Demethyl-3\"-N-substituted-4,6-di-0-(aminoglycosyl)-1,3-diaminocyclitols, methods for their preparation and their application as antibiotics | BAYER AG (DE) | 1979-03-07 | — | — | EP | disclosed |