⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992 | 0.93 | — | — | |
| SCHEMBL30487170 | 0.93 | — | — | |
| SCHEMBL2686745 | 0.93 | — | — | |
| SCHEMBL2713018 | 0.93 | — | — | |
| SCHEMBL11485188 | 0.93 | TSHR (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL2909006 | 0.89 | — | — | |
| Isobutane SCHEMBL3410753 | 0.89 | TSHR (0.31) | — | |
| Iodide SCHEMBL31325854 | 0.89 | — | — | |
| Methane SCHEMBL11669299 | 0.89 | — | — | |
| Water SCHEMBL29494590 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6607893-B2 | Measuring diacylglycerol acetyltransferase activity; obtain enzmatic substrate, expose to microsomes, terminate reaction, monitor triglyceride generation | WARNER-LAMBERT COMPANY | 2003-08-19 | — | — | US | disclosed |
| US-20020127627-A1 | Diacylglycerol acyltransferase (DGAT) assay | RAMHARACK RANDY RANJEE (US) | 2002-09-12 | — | — | US | disclosed |
| EP-1219716-A2 | Diacylglycerol acyltransferase (DGAT) assay | WARNER-LAMBERT COMPANY (US) | 2002-07-03 | — | — | EP | disclosed |