SCHEMBL7212822

SCHEMBL7212822

COc1cc(-c2cccs2)c(OC)c2c(OC)cc(-c3cccs3)c(OC)c12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RPS6KB2 Q9UBS0 2/20 0.49
SMN1; SMN2 Q16637 4/20 0.48
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 3/20 0.48
KDM4E B2RXH2 2/20 0.48
GAA P10253 2/20 0.48
HPGD P15428 1/20 0.48
ERN1 O75460 1/20 0.47
MAPT P10636 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPK1 P28482 2/20 0.46
IDO1 P14902 1/20 0.46
TDO2 P48775 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
TUBB4A P04350 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2780877 0.83 RPS6KB2 (0.56) RPS6KB2SMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL18133657 0.77 ERN1 (0.50) RPS6KB2SMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL27601843 0.77 ERN1 (0.55) RPS6KB2SMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL28672054 0.77 SMN1; SMN2 (0.49) RPS6KB2SMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL7213105 0.77 ERN1 (0.58) RPS6KB2SMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL6094859 0.76 CYP1A2 (0.46) RPS6KB2SMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL6067795 0.76 ERN1 (0.54) RPS6KB2SMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL6040526 0.75 TNFRSF1A (0.55) RPS6KB2SMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL6090955 0.75 TNFRSF1A (0.47) RPS6KB2SMN1; SMN2ALDH1A1HSD17B10KDM4E
SCHEMBL26259904 0.75 RPS6KB2 (0.56) RPS6KB2SMN1; SMN2ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6617462-B1 Di- and tetra-methoxy-bis(2-thienyl)naphthalene monomers that can be electropolymerized to form conductive polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2003-09-09 US claimed
US-6617462-B1 Di- and tetra-methoxy-bis(2-thienyl)naphthalene monomers that can be electropolymerized to form conductive polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2003-09-09 US disclosed
US-6359149-B1 Bithienylnaphthalene- and bis(3,4-ethylenedioxythienyl)naphthalene-based monomers and polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2002-03-19 US disclosed
US-6291621-B1 FOR PRODUCING THIN FILMS AND COATINGS USEFUL IN ELECTROCHROMIC APPLICATIONS; ELECTROCONDUCTIVITY, ELECTRODES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2001-09-18 US disclosed