Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.50 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | QDPR | P09417 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212851 | 1.00 | DPP4 (0.50) | DPP4KDM1AALDH1A1KDM4EMAPT | |
| SCHEMBL7212853 | 1.00 | DPP4 (0.50) | DPP4KDM1AALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7205700 | 0.99 | DPP4 (0.49) | DPP4KDM1AALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7205705 | 0.99 | DPP4 (0.49) | DPP4KDM1AALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7205702 | 0.99 | DPP4 (0.49) | DPP4KDM1AALDH1A1KDM4EMAPT | |
| SCHEMBL6441313 | 0.95 | DPP4 (0.50) | DPP4KDM1AALDH1A1HPGDQDPR | |
| SCHEMBL6441317 | 0.95 | DPP4 (0.50) | DPP4KDM1AALDH1A1HPGDQDPR | |
| SCHEMBL6441320 | 0.95 | DPP4 (0.50) | DPP4KDM1AALDH1A1HPGDQDPR | |
| Hydrochloric Acid SCHEMBL6438947 | 0.94 | DPP4 (0.49) | DPP4KDM1AMEN1KMT2AQDPR | |
| Hydrochloric Acid SCHEMBL6438943 | 0.94 | DPP4 (0.49) | DPP4KDM1AMEN1KMT2AQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968211-B1 | TETRAZOLE DERIVATIVES | ALTANA PHARMA AG (DE) | 2003-08-27 | — | — | EP | disclosed |
| US-6143759-A | ANTIINFLAMMATORY AGENTS AND ANTICOAGULANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-11-07 | — | — | US | disclosed |
| EP-0968211-A1 | NOVEL TETRAZOLES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998040382-A1 | NOVEL TETRAZOLES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |