Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351756 | 0.92 | TACR1 (0.52) | TACR1SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL8664555 | 0.91 | TACR1 (0.48) | TACR1SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL9540221 | 0.88 | TACR1 (0.48) | TACR1CMA1ACE | |
| SCHEMBL15231906 | 0.88 | SLC6A2 (0.59) | SLC6A2OPRM1OPRD1OPRK1CMA1 | |
| SCHEMBL15231898 | 0.88 | SLC6A2 (0.59) | SLC6A2OPRM1OPRD1OPRK1CMA1 | |
| SCHEMBL15231343 | 0.88 | SLC6A2 (0.59) | SLC6A2OPRM1OPRD1OPRK1CMA1 | |
| SCHEMBL10297414 | 0.83 | ACE (0.51) | OPRM1OPRD1OPRK1CMA1ACE | |
| SCHEMBL14479876 | 0.83 | ACE (0.51) | OPRM1OPRD1OPRK1CMA1ACE | |
| SCHEMBL4959360 | 0.83 | ACE (0.51) | OPRM1OPRD1OPRK1CMA1ACE | |
| SCHEMBL5062693 | 0.81 | TACR1 (0.43) | TACR1SLC6A2OPRM1CMA1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303582-A2 | STABILIZATION OF ENZYMES | GENENCOR INTERNATIONAL, INC. (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008398-A2 | STABILIZATION OF ENZYMES | GENENCOR INTERNATIONAL, INC. (US) | 2002-01-31 | — | — | WO | disclosed |