Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.47 |
| ▸ | F2 | P00734 | 6/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7213654 | 1.00 | F10 (0.47) | F10F2DPP4DPP7KLKB1 | |
| SCHEMBL23752546 | 0.93 | F10 (0.52) | F10F2KLKB1PRSS1DGAT1 | |
| SCHEMBL6222403 | 0.93 | F10 (0.52) | F10F2KLKB1PRSS1DGAT1 | |
| Trifluoroacetic Acid SCHEMBL7214503 | 0.93 | F10 (0.47) | F10F2KLKB1 | |
| Hydrochloric Acid SCHEMBL6434810 | 0.92 | F10 (0.51) | F10F2KLKB1PRSS1DGAT1 | |
| Trifluoroacetic Acid SCHEMBL7213657 | 0.89 | F10 (0.48) | F10F2DPP4DPP7KLKB1 | |
| Trifluoroacetic Acid SCHEMBL7213717 | 0.89 | F10 (0.48) | F10F2DPP4DPP7KLKB1 | |
| Trifluoroacetic Acid SCHEMBL7540260 | 0.89 | F10 (0.48) | F10F2DPP4DPP7KLKB1 | |
| Trifluoroacetic Acid SCHEMBL7215791 | 0.87 | F10 (0.47) | F10F2DPP4DPP7KLKB1 | |
| Trifluoroacetic Acid SCHEMBL7414635 | 0.86 | F10 (0.47) | F10F2DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602864-B1 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-05 | — | — | US | claimed |
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | claimed |
| US-6602864-B1 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | disclosed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |
| WO-2001039759-A2 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |