Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578812 | 0.94 | KDM1A (0.59) | KDM1ATSHRMEN1KMT2ASIGMAR1 | |
| SCHEMBL29556050 | 0.94 | KDM1A (0.59) | KDM1ATSHRMEN1KMT2ASIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL27728989 | 0.92 | KDM1A (0.58) | KDM1ATSHRMEN1KMT2ASIGMAR1 | |
| Methyl Alcohol SCHEMBL14815563 | 0.90 | KDM1A (0.56) | KDM1AMEN1KMT2ASIGMAR1HDAC9 | |
| Bicarbonate SCHEMBL28494150 | 0.85 | KDM1A (0.51) | KDM1ATSHRMEN1KMT2ASIGMAR1 | |
| Ethylene Glycol SCHEMBL870255 | 0.85 | KDM1A (0.51) | KDM1ATSHRMEN1KMT2ASIGMAR1 | |
| SCHEMBL29529565 | 0.85 | KDM1A (0.48) | KDM1ATSHRMEN1KMT2AHDAC9 | |
| SCHEMBL412891 | 0.85 | KDM1A (0.48) | KDM1ATSHRMEN1KMT2AHDAC9 | |
| SCHEMBL27908726 | 0.85 | KDM1A (0.48) | KDM1ATSHRMEN1KMT2AHDAC9 | |
| Hydrochloric Acid SCHEMBL27330764 | 0.83 | KDM1A (0.47) | KDM1ATSHRMEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610877-B1 | Treating photo and/or age damaged skin | HOFFMAN-LA ROCHE INC. | 2003-08-26 | — | — | US | disclosed |
| EP-0641759-B1 | Use of aromatic carboxylic derivatives for the preparation of drugs | HOFFMANN LA ROCHE (CH) | 1998-12-09 | — | — | EP | disclosed |
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |
| EP-0641759-A1 | Aromatic carboxylic acid derivatives, their preparation and drugs containing these derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1995-03-08 | — | — | EP | disclosed |