SCHEMBL7214049

SCHEMBL7214049

O=P(O)(O)OP(=O)(O)CCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
CYP2D6 P10635 1/20 0.50
POLB P06746 1/20 0.49
CETP P11597 4/20 0.47
SRC P12931 1/20 0.45
ANPEP P15144 2/20 0.44
ERAP1 Q9NZ08 2/20 0.44
ERAP2 Q6P179 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP3 P08254 1/20 0.43
CA9 Q16790 1/20 0.43
ACP3 P15309 1/20 0.43
S1PR2 O95136 1/20 0.42
S1PR4 O95977 1/20 0.42
S1PR1 P21453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL27594654 0.84 TSHR (0.53) TSHRCYP2D6POLBSRCANPEP
SCHEMBL3404561 0.81 TSHR (0.56) TSHRPOLBCETPCA12CA1
SCHEMBL28153833 0.81 TSHR (0.56) TSHRCYP2D6POLBCETPANPEP
SCHEMBL28673887 0.81 TSHR (0.56) TSHRCYP2D6POLBCETPANPEP
SCHEMBL25308000 0.79 TSHR (0.55) TSHRCYP2D6POLBCETPANPEP
SCHEMBL1101314 0.77 TSHR (0.67) TSHRCYP2D6POLBCETPANPEP
SCHEMBL6030731 0.77 TSHR (0.88) TSHRCYP2D6POLBCETPANPEP
Pyrophosphoric Acid SCHEMBL30274280 0.77 TDP1 (0.61) TSHRCYP2D6POLBSRCANPEP
SCHEMBL12030480 0.77 TSHR (0.51) TSHRCYP2D6POLBCETPANPEP
SCHEMBL2517900 0.75 TSHR (0.84) TSHRCYP2D6POLBCETPANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1292662-A2 RINSE-ADDED FABRIC TREATMENT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2003-03-19 EP disclosed
WO-2001098447-A2 RINSE-ADDED FABRIC TREATMENT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2001-12-27 WO disclosed