Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.94 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | CES1 | P23141 | 2/20 | 0.67 |
| ▸ | CES2 | O00748 | 1/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | PAM | P19021 | 2/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylacetic Acid SCHEMBL4982826 | 1.00 | AKR1B1 (0.94) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL7880820 | 1.00 | AKR1B1 (0.94) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL11130707 | 1.00 | AKR1B1 (0.94) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL28201214 | 0.97 | AKR1B1 (0.90) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL28843890 | 0.97 | AKR1B1 (0.90) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL28215596 | 0.97 | AKR1B1 (0.90) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL1330777 | 0.97 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL28242469 | 0.97 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL13618842 | 0.97 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL9449909 | 0.97 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100356916-C | Pharmaceutical compositions | LILLY CO ELI (US) | 2007-12-26 | — | — | CN | disclosed |
| EP-0857788-B1 | Method for producing nucleoside-5'-phosphate ester | AJINOMOTO KK (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6355472-B2 | ACID PHOSPHATASE | AJINOMOTO CO., INC. (JP) | 2002-03-12 | — | — | US | disclosed |
| US-20020004590-A1 | Method for producing nucleoside-5'-phosphate ester | MIHARA YASUHIRO (JP) | 2002-01-10 | — | — | US | disclosed |
| US-6207435-B1 | MUTANT ACID PHOSPHATASE HAVING DECREASED MICHAELIS CONSTANT FOR A NUCLEOSIDE AND/OR INCREASED TEMPERATURE STABILITY; FOR EFFICIENT PHOSPHORYLATION OF NUCLEOSIDES TO PRODUCE NUCLEOTIDES | AJINOMOTO CO., INC. (JP) | 2001-03-27 | — | — | US | disclosed |
| US-6015697-A | ECONOMICAL AND EFFICIENT PROCESS BY REACTING A NUCLEOSIDE WITH A PHOSPHATE DONOR GROUP IN PRESENCE OF MUTANT ACID PHOSPHATASE WITH DECREASED MICHAELIS CONSTANT FOR NUCLEOSIDE OR INCREASED TEMPERATURE STABILITY | AJINOMOTO CO., INC. (JP) | 2000-01-18 | — | — | US | disclosed |
| CN-1233957-A | Pharmaceutical compositions | LILLY CO ELI (US) | 1999-11-03 | — | — | CN | disclosed |
| EP-0857788-A2 | Method for producing nucleoside-5'-phosphate ester | Ajinomoto Co., Inc. (JP) | 1998-08-12 | — | — | EP | disclosed |
| CN-1021720-C | Agricultural composition containing acrylic acid derivative as active ingredient, its use and preparation method | ICI PLC (GB) | 1993-08-04 | — | — | CN | disclosed |
| CN-87103623-A | Fungicidal agents | ICI PLC (GB) | 1988-02-24 | — | — | CN | disclosed |
| EP-0007690-B1 | PROCESS FOR THE PRODUCTION OF A POLYSACCHARIDE | TATE & LYLE PATENT HOLDINGS LIMITED (BM) | 1982-10-06 | — | — | EP | disclosed |
| US-4296112-A | ANTIBACTERIAL | MITSUI TOATSU CHEMICALS, INC. (JP) | 1981-10-20 | — | — | US | disclosed |
| US-4283398-A | Cephalosporins | MITSUI TOATSU CHEMICALS, INC. (JP) | 1981-08-11 | — | — | US | disclosed |
| US-4263302-A | ANTIBIOTICS EFFECTIVE AGAINST PSEUDOMONAS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1981-04-21 | — | — | US | disclosed |
| US-4235966-A | FROM D-MANNURONIC AND L-GULURONIC ACID RESIDUES | TALRES DEVELOPMENT (N.A.) N.V. (AN) | 1980-11-25 | — | — | US | disclosed |
| EP-0007690-A1 | Process for the production of a polysaccharide | TATE & LYLE PATENT HOLDINGS LIMITED (BM) | 1980-02-06 | — | — | EP | disclosed |