Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.71 |
| ▸ | PPARG | P37231 | 1/20 | 0.71 |
| ▸ | PPARD | Q03181 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774701 | 0.92 | PPARA (0.73) | PPARAPPARGPPARDRAB9A | |
| Hydrochloric Acid SCHEMBL6784678 | 0.91 | PPARA (0.72) | PPARAPPARGPPARDRAB9A | |
| SCHEMBL6781039 | 0.89 | PPARA (0.67) | PPARAPPARGPPARDRAB9ANPC1 | |
| SCHEMBL6781092 | 0.89 | PPARA (0.69) | PPARAPPARGPPARDRAB9ANPC1 | |
| SCHEMBL6774636 | 0.87 | PPARA (0.64) | PPARAPPARGPPARDRAB9A | |
| SCHEMBL6778785 | 0.85 | PPARA (0.77) | PPARAPPARGPPARDRAB9A | |
| SCHEMBL6778683 | 0.85 | PPARA (0.63) | PPARAPPARGPPARDRAB9ANPSR1 | |
| SCHEMBL6778216 | 0.84 | PPARA (0.63) | PPARAPPARGPPARD | |
| SCHEMBL7212950 | 0.84 | PPARA (0.71) | PPARAPPARGPPARDRAB9A | |
| SCHEMBL6781210 | 0.83 | PPARA (1.00) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328508-A2 | PROPIONIC ACID DERIVATIVES WITH PPAR-ALPHA ACTIVATING PROPERTIES | Bayer Aktiengesellschaft (DE) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002028821-A2 | PROPIONIC ACID DERIVATIVES WITH PPAR-ALPHA ACTIVATING PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-11 | — | — | WO | disclosed |