SCHEMBL7214796

SCHEMBL7214796

CCOP(=O)(OCC)c1ccc(C(=O)O)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.46
TSHR P16473 1/20 0.46
CASP1 P29466 1/20 0.46
KMT2A Q03164 6/20 0.43
MEN1 O00255 5/20 0.43
TDP1 Q9NUW8 2/20 0.43
NR1I2 O75469 1/20 0.43
MYC P01106 1/20 0.41
NR4A1 P22736 1/20 0.41
NR1H4 Q96RI1 1/20 0.39
ALDH1A1 P00352 4/20 0.38
MAPT P10636 2/20 0.38
ABL1 P00519 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
RIN1 Q13671 1/20 0.38
P2RY1 P47900 1/20 0.38
POLB P06746 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8419111 0.78 MEN1 (0.36) TSHRKMT2AMEN1ALDH1A1GAA
SCHEMBL7209760 0.78 MAPT (0.42) SMN1; SMN2TSHRKMT2AMEN1TDP1
SCHEMBL2207123 0.74 MEN1 (0.50) SMN1; SMN2TSHRKMT2AMEN1TDP1
SCHEMBL6829825 0.72 TDP1 (0.49) TSHRKMT2AMEN1TDP1POLB
SCHEMBL11809413 0.71 MEN1 (0.41) SMN1; SMN2KMT2AMEN1NR1I2ALDH1A1
SCHEMBL5032922 0.71 KDM4E (0.53) SMN1; SMN2TSHRCASP1KMT2AMEN1
SCHEMBL914851 0.71 POLB (0.47) SMN1; SMN2KMT2AMEN1TDP1NR1I2
SCHEMBL11873114 0.70 CYP2C9 (0.41) TSHRKMT2AMEN1ALDH1A1MAPT
SCHEMBL916035 0.69 NPSR1 (0.47) KMT2AMEN1TDP1NR1I2LMNA
SCHEMBL31688379 0.69 NPSR1 (0.47) KMT2AMEN1TDP1NR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6613717-B1 Phosphoric benzoyl derivatives and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2003-09-02 US disclosed
EP-1173449-A1 PHOSPHORIC BENZOYL DERIVATIVES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2002-01-23 EP disclosed
WO-2000064912-A1 PHOSPHORIC BENZOYL DERIVATIVES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-11-02 WO disclosed