Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272420 | 0.97 | TSHR (0.39) | TSHR | |
| Hydrochloric Acid SCHEMBL11584438 | 0.94 | TSHR (0.37) | TSHR | |
| Water SCHEMBL319988 | 0.94 | TSHR (0.37) | TSHR | |
| Hydrochloric Acid SCHEMBL27408053 | 0.91 | TSHR (0.35) | TSHR | |
| SCHEMBL9003640 | 0.86 | TSHR (0.38) | TSHR | |
| Acetic Acid SCHEMBL320011 | 0.84 | CA1 (0.40) | TSHR | |
| SCHEMBL8023577 | 0.75 | TDP1 (0.37) | TSHR | |
| SCHEMBL27840696 | 0.75 | — | — | |
| SCHEMBL11706248 | 0.73 | TSHR (0.41) | TSHR | |
| SCHEMBL15611974 | 0.73 | TSHR (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107151288-A | It is a kind of for flotation agent of middle matter crude oil and preparation method thereof | 天津亿利科能源科技发展股份有限公司 | 2017-09-12 | — | — | CN | disclosed |
| US-6616920-B1 | Copolymer of an acrylated or styrenized polysiloxane and a radical polymerizable monomer, especially an acrylic monomer containing an amine oxide or quaternium ammonium internal salt. | MITSUBISHI CHEMICAL AMERICA, INC. | 2003-09-09 | — | — | US | disclosed |
| US-5362485-A | For setting or conditioning hair; softness, luster | MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0165333-B1 | NEW COMPOUNDS CONTAINING QUATERNARY AMMONIUM AND METHYLENEPHOSPHONIC ACID GROUPS | THE DOW CHEMICAL COMPANY (US) | 1989-02-08 | — | — | EP | disclosed |
| US-4493771-A | Scale inhibiting with compounds containing quaternary ammonium and methylenephosphonic acid groups | THE DOW CHEMICAL COMPANY (US) | 1985-01-15 | — | — | US | disclosed |
| US-4459241-A | ANTIDEPOSIT AGENTS | THE DOW CHEMICAL COMPANY (US) | 1984-07-10 | — | — | US | disclosed |