Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502978 | 0.92 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR6OPRL1 | |
| SCHEMBL7211577 | 0.82 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL7214937 | 0.81 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL5829578 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR6ALDH1A1 | |
| SCHEMBL5830166 | 0.76 | SLC6A4 (0.59) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL6499524 | 0.74 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL7210324 | 0.74 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ALDH1A1CNR2 | |
| SCHEMBL7209988 | 0.74 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7210016 | 0.74 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5829673 | 0.71 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984966-B1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH AS (DK) | 2003-01-29 | — | — | EP | claimed |
| US-6392045-B1 | 9-azobicyclo[3.3.1] non-2-ene derivatives as cholinergic ligands at nicotinic ACH receptors | NEUROSEARCH A/S (DK) | 2002-05-21 | — | — | US | claimed |
| EP-0984966-A1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH A/S (DK) | 2000-03-15 | — | — | EP | claimed |
| WO-1998054182-A1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH A/S (DK) | 1998-12-03 | — | — | WO | claimed |
| EP-0984966-B1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH AS (DK) | 2003-01-29 | — | — | EP | disclosed |
| US-6392045-B1 | 9-azobicyclo[3.3.1] non-2-ene derivatives as cholinergic ligands at nicotinic ACH receptors | NEUROSEARCH A/S (DK) | 2002-05-21 | — | — | US | disclosed |
| EP-0984966-A1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH A/S (DK) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054182-A1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH A/S (DK) | 1998-12-03 | — | — | WO | disclosed |