Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7222296 | 0.82 | MAPK14 (0.43) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7215202 | 0.82 | MAPK14 (0.46) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6075875 | 0.79 | MAPK14 (0.50) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5771460 | 0.78 | MAPK14 (0.40) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5771176 | 0.78 | MAPK14 (0.40) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5772045 | 0.78 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6808788 | 0.77 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7217798 | 0.77 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5772812 | 0.77 | MAPK14 (0.39) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5773935 | 0.76 | MAPK13 (0.55) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |