Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ADH1A | P07327 | 3/20 | 0.32 |
| ▸ | ADH1C | P00326 | 2/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexanol SCHEMBL28263893 | 0.81 | TSHR (0.59) | TSHRADH1AADH1CADH1BADH4 | |
| Cyclohexanol SCHEMBL27988058 | 0.80 | TSHR (0.50) | TSHRADH1AADH1CADH1BADH4 | |
| Cyclohexanol SCHEMBL28111021 | 0.78 | TSHR (0.62) | TSHRADH1AADH1CADH1BADH4 | |
| Cyclopentane SCHEMBL1050729 | 0.78 | — | — | |
| SCHEMBL4966548 | 0.78 | — | — | |
| Cyclopentanol SCHEMBL27867711 | 0.77 | TSHR (0.53) | TSHRADH1AADH1C | |
| Cyclopentanol SCHEMBL27942224 | 0.75 | — | — | |
| Cyclopentanol SCHEMBL28852659 | 0.75 | TSHR (0.50) | TSHRADH1AADH1C | |
| SCHEMBL23121456 | 0.74 | TSHR (0.91) | TSHRCES2CES1 | |
| SCHEMBL11948482 | 0.74 | TSHR (0.91) | TSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251846-A4 | C-4 CARBONATE TAXANES | BRISTOL MYERS SQUIBB CO (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1251846-A1 | C-4 CARBONATE TAXANES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001056565-A1 | C-4 CARBONATE TAXANES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |