Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | F11 | P03951 | 2/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263978 | 1.00 | PTPN1 (0.47) | PTPN1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL7215485 | 1.00 | PTPN1 (0.47) | PTPN1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL5974836 | 1.00 | PTPN1 (0.47) | PTPN1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL4263976 | 1.00 | PTPN1 (0.47) | PTPN1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL6377056 | 1.00 | PTPN1 (0.47) | PTPN1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL8390475 | 1.00 | PTPN1 (0.47) | PTPN1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL6377053 | 1.00 | PTPN1 (0.47) | PTPN1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL5974842 | 1.00 | PTPN1 (0.47) | PTPN1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL22758821 | 1.00 | PTPN1 (0.47) | PTPN1TSHRKMT2AUSP2MEN1 | |
| SCHEMBL6377061 | 1.00 | PTPN1 (0.47) | PTPN1TSHRKMT2AUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1295890-A1 | Novel pyrazine derivatives or salts thereof, pharmaceutical composition containing the same, and production intermediates thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| EP-1256588-A1 | NOVEL PYRAZINE DERIVATIVES OR SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THE DERIVATIVES OR THE SALTS AND INTERMEDIATES FOR THE PREPARATION OF BOTH | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |