Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.57 |
| ▸ | PDE4A | P27815 | 19/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13526155 | 0.91 | PDE4B (0.67) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3176101 | 0.88 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3160359 | 0.87 | PDE4B (0.69) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7215575 | 0.84 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3166256 | 0.82 | PDE4A (0.82) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3181091 | 0.82 | PDE4A (0.79) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3976093 | 0.81 | PDE4B (0.72) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13526248 | 0.79 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3175816 | 0.78 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL3160593 | 0.77 | PDE4B (0.72) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308440-A1 | PIPERIDINE DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-07 | — | — | EP | claimed |
| EP-1308440-A1 | PIPERIDINE DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-07 | — | — | EP | disclosed |