SCHEMBL7216690

CCOP(=O)(OCC)C(c1ccc(C[C@H](N)C(=O)N[C@@H](C)c2ccc(OCC3CCCCC3)c(C(N)=O)c2)cc1)P(=O)(OCC)OCC

nearest known ligand 0.71

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	SRC	P12931	18/20	0.71

▸	YES1	P07947	2/20	0.65

▸	IRAK4	Q9NWZ3	1/20	0.38

▸	PARP15	Q460N3	1/20	0.37

▸	PARP10	Q53GL7	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7220482	0.93	SRC (0.83)	SRCYES1
SCHEMBL7216862	0.89	SRC (0.88)	SRCYES1
SCHEMBL7214473	0.88	SRC (0.69)	SRCYES1
SCHEMBL7216753	0.84	SRC (0.74)	SRCYES1
SCHEMBL7221403	0.83	SRC (1.00)	SRCYES1
SCHEMBL7661502	0.82	SRC (0.64)	SRCYES1PARP15PARP10
SCHEMBL7216858	0.82	SRC (0.85)	SRCYES1
SCHEMBL7216751	0.80	SRC (0.72)	SRCYES1
SCHEMBL8419506	0.80	SRC (0.85)	SRCYES1
SCHEMBL8419505	0.80	SRC (0.85)	SRCYES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6576766-B1	Competitive binding of phosphotyrosine-containing protein; veterinary medicine	ARIAD PHARMACEUTICALS, INC.	2003-06-10	—	—	US	disclosed