⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3014158 | 0.67 | — | — | |
| SCHEMBL7223300 | 0.64 | — | — | |
| SCHEMBL6678620 | 0.58 | — | — | |
| SCHEMBL127486 | 0.55 | — | — | |
| SCHEMBL1752177 | 0.55 | — | — | |
| SCHEMBL212950 | 0.52 | — | — | |
| SCHEMBL984941 | 0.52 | — | — | |
| Hydrochloric Acid SCHEMBL7635615 | 0.52 | — | — | |
| SCHEMBL6862722 | 0.52 | — | — | |
| SCHEMBL1354775 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632015-A | Method for preparing drug Roflumilast for treating chronic obstructive pulmonary disease | 中国科学院成都有机化学有限公司 | 2017-05-10 | — | — | CN | claimed |
| EP-4281456-A1 | NOVEL BICYCLIC COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2023-11-29 | — | — | EP | disclosed |
| US-20230374034-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-11-23 | — | — | US | disclosed |
| WO-2023200017-A1 | NOVEL SEVEN-MEMBERED RING-FUSED COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-10-19 | — | — | WO | disclosed |
| CN-116710455-A | Novel bicyclic compounds | 株式会社棱镜生物实验室 | 2023-09-05 | — | — | CN | disclosed |
| US-20230265104-A1 | NOVEL HETEROCYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-08-24 | — | — | US | disclosed |
| EP-4225760-A1 | NOVEL BICYCLIC COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2023-08-16 | — | — | EP | disclosed |
| WO-2023140369-A1 | PHOSPHORIC ACID DERIVATIVES | Prism BioLab Co., Ltd. (JP) | 2023-07-27 | — | — | WO | disclosed |
| CN-116348119-A | Novel bicyclic compounds | 株式会社棱镜生物实验室 | 2023-06-27 | — | — | CN | disclosed |
| EP-4182317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2023-05-24 | — | — | EP | disclosed |
| CN-116018345-A | Novel heterocyclic compounds | 株式会社棱镜生物实验室 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022075486-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2022-04-14 | — | — | WO | disclosed |
| WO-2022014724-A1 | NOVEL HETEROCYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2022-01-20 | — | — | WO | disclosed |
| CN-106632015-A | Method for preparing drug Roflumilast for treating chronic obstructive pulmonary disease | 中国科学院成都有机化学有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-102439008-B | 1,2, 4-triazolo [4,3-a ] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders | ORTHO MCNEIL JANSSEN PHARM | 2015-04-29 | — | — | CN | disclosed |
| CN-1193020-C | Process for preparing amic acid esters | IHARA CHEMICAL IND CO (JP) | 2005-03-16 | — | — | CN | disclosed |
| US-6576765-B2 | Process for preparing amic acid esters | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| US-20030032667-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-02-13 | — | — | US | disclosed |
| CN-1366523-A | Process for preparing amic acid esters | IHARA CHEMICAL IND CO (JP) | 2002-08-28 | — | — | CN | disclosed |
| EP-1182199-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |