Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.66 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | TACR2 | P21452 | 2/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217580 | 0.90 | CNR2 (0.69) | CNR2CNR1TACR2TRPV4CYP3A4 | |
| SCHEMBL7223448 | 0.81 | CNR2 (0.65) | CNR2CNR1TACR2TRPV4CYP3A4 | |
| SCHEMBL7224460 | 0.79 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL7216928 | 0.77 | CNR2 (0.84) | CNR2CNR1 | |
| SCHEMBL7218591 | 0.77 | CNR2 (0.81) | CNR2CNR1POLB | |
| SCHEMBL7216755 | 0.77 | CNR2 (0.81) | CNR2CNR1CYP3A4 | |
| SCHEMBL7224182 | 0.77 | CNR2 (0.61) | CNR2CNR1TACR2CYP3A4CYP2D6 | |
| SCHEMBL7218551 | 0.76 | CNR2 (0.60) | CNR2CNR1TACR2TRPV4 | |
| SCHEMBL7217492 | 0.76 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL7223450 | 0.76 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653304-B2 | Antiarthritic agents; skin disorders; anticarcinogenic agents | BRISTOL-MYERS SQUIBB CO. | 2003-11-25 | — | — | US | disclosed |