Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.63 |
| ▸ | F10 | P00742 | 2/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854825 | 0.91 | F2 (0.64) | F2F10 | |
| SCHEMBL5856832 | 0.86 | F2 (0.59) | F2F10 | |
| SCHEMBL5475016 | 0.83 | F2 (0.56) | F2F10 | |
| SCHEMBL7372745 | 0.81 | F2 (0.75) | F2PRSS1 | |
| SCHEMBL7371327 | 0.79 | F2 (0.73) | F2F10PRSS1 | |
| SCHEMBL5858376 | 0.78 | F2 (1.00) | F2F10 | |
| Trifluoroacetic Acid SCHEMBL5856894 | 0.76 | F2 (0.94) | F2F10 | |
| SCHEMBL14508709 | 0.75 | F2 (0.62) | F2F10PRSS1 | |
| SCHEMBL5856139 | 0.75 | F2 (1.00) | F2F10PRSS1 | |
| SCHEMBL5855753 | 0.75 | F2 (1.00) | F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359913-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002064140-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |