Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 19/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218488 | 0.91 | GAA (0.40) | LSSMEN1KMT2A | |
| SCHEMBL7217087 | 0.87 | LSS (0.35) | LSS | |
| SCHEMBL7218485 | 0.86 | LSS (0.36) | LSSMEN1KMT2A | |
| SCHEMBL7218501 | 0.86 | LSS (0.45) | LSS | |
| SCHEMBL7218473 | 0.85 | LSS (0.41) | LSSMEN1KMT2A | |
| SCHEMBL7212168 | 0.85 | LSS (0.47) | LSSMEN1KMT2A | |
| SCHEMBL7218497 | 0.85 | LSS (0.47) | LSSMEN1KMT2A | |
| SCHEMBL7218354 | 0.83 | HDAC8 (0.35) | LSSMEN1KMT2A | |
| SCHEMBL7218464 | 0.82 | LSS (0.41) | LSSMEN1KMT2A | |
| SCHEMBL7213266 | 0.82 | LSS (0.35) | LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358162-A1 | DIHYDROINDOLE AND TETRAHYDROQUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002050041-A1 | DIHYDROINDOLE AND TETRAHYDROQUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-27 | — | — | WO | disclosed |