SCHEMBL7217538

SCHEMBL7217538

COc1ccc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)c(C)c1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SSTR1 P30872 1/20 0.44
SSTR2 P30874 1/20 0.44
SSTR4 P31391 1/20 0.44
SSTR3 P32745 1/20 0.44
SSTR5 P35346 1/20 0.44
PTPN1 P18031 8/20 0.41
PTPN2 P17706 3/20 0.41
HTR1A P08908 1/20 0.41
TACR2 P21452 3/20 0.41
CDC25B P30305 6/20 0.40
PTPN6 P29350 2/20 0.40
PTPN11 Q06124 2/20 0.40
GJB2 P29033 1/20 0.39
NT5E P21589 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673932 0.90 SSTR1 (0.45) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL28411979 0.82 SSTR1 (0.47) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL5275031 0.80 TACR2 (0.45) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL20558600 0.79 SLC5A1 (0.49)
SCHEMBL19123820 0.79 SLC5A1 (0.49)
SCHEMBL16715316 0.79 SLC5A2 (0.57)
SCHEMBL7222328 0.78 SSTR1 (0.48) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL5275024 0.78 SSTR1 (0.42) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL5271246 0.78 PTPN1 (0.44) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL14795427 0.78 PTPN1 (0.46) SSTR1SSTR2SSTR4SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6627611-B2 Reacting a acetophenyl derivative with an aromatic aldehyde or heterocylic containing aldehyde derivative by aldol condentation followed by reduction KOTOBUKI PHARMACEUTICAL CO LTD (JP) 2003-09-30 US disclosed
US-20010041674-A1 C-glycosides and preparation of thereof as antidiabetic agents KOTOBUJKI PHARMACEUTICAL CO., LTD. 2001-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010041674-A1 C-glycosides and preparation of thereof as antidiabetic agents GCG, SLC5A1, SLC5A2 SSTR1 410/4885SSTR2 445/4885SSTR4 771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.