Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 11/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773214 | 0.94 | MAPK14 (0.62) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5767083 | 0.88 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5771364 | 0.87 | MAPK14 (0.63) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5766667 | 0.87 | MAPK14 (0.60) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5769620 | 0.86 | MAPK14 (0.68) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5771725 | 0.86 | MAPK14 (0.64) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5770633 | 0.85 | MAPK14 (0.60) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5770114 | 0.85 | MAPK13 (0.63) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5768914 | 0.85 | MAPK13 (0.63) | MAPK13MAPK12MAPK11MAPK14BRAF | |
| SCHEMBL5771678 | 0.85 | MAPK13 (0.66) | MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |