Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | SOAT1 | P35610 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225461 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2SOAT1KMT2AMEN1TDP1 | |
| SCHEMBL7225138 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7223109 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2TDP1LMNAALDH1A1HTT | |
| SCHEMBL190379 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2SOAT1KMT2AMEN1TDP1 | |
| SCHEMBL10948543 | 0.74 | SMN1; SMN2 (0.82) | SMN1; SMN2SOAT1KMT2AMEN1TDP1 | |
| SCHEMBL7219654 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7218471 | 0.71 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7225295 | 0.70 | SMN1; SMN2 (0.75) | SMN1; SMN2SOAT1KMT2AMEN1TDP1 | |
| SCHEMBL7219261 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL9843936 | 0.68 | SMN1; SMN2 (0.77) | SMN1; SMN2SOAT1KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |