SCHEMBL721851

SCHEMBL721851

CCCCCCCCCCc1c(CCC(C)C)ccc(C(=O)O)c1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.44
KAT8 Q9H7Z6 5/20 0.44
BID P55957 3/20 0.44
MCL1 Q07820 3/20 0.44
PPARG P37231 3/20 0.44
BCL2L1 Q07817 2/20 0.44
BAK1 Q16611 2/20 0.44
EP300 Q09472 2/20 0.44
KAT5 Q92993 2/20 0.44
KAT2A Q92830 1/20 0.44
KAT2B Q92831 1/20 0.44
SAE1 Q9UBE0 1/20 0.44
RARB P10826 3/20 0.43
ALDH1A1 P00352 1/20 0.40
RARA P10276 1/20 0.40
RARG P13631 1/20 0.40
PLK1 P53350 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721060 1.00 PPARA (0.44) PPARAKAT8BIDMCL1PPARG
SCHEMBL721059 0.95 PPARA (0.47) PPARAKAT8BIDMCL1PPARG
SCHEMBL721850 0.95 PPARA (0.47) PPARAKAT8BIDMCL1PPARG
SCHEMBL721671 0.94 PPARA (0.46) PPARAKAT8BIDMCL1PPARG
SCHEMBL724432 0.94 PPARA (0.46) PPARAKAT8BIDMCL1PPARG
SCHEMBL722357 0.94 PPARA (0.46) PPARAKAT8BIDMCL1PPARG
SCHEMBL29884328 0.94 PPARA (0.46) PPARAKAT8BIDMCL1PPARG
SCHEMBL29763192 0.94 PPARA (0.46) PPARAKAT8BIDMCL1PPARG
SCHEMBL16295022 0.93 PPARA (0.45) PPARAKAT8BIDMCL1PPARG
SCHEMBL722551 0.92 PPARA (0.44) PPARAKAT8BIDMCL1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8648001-B2 Aminosilane compounds, catalyst components and catalysts for olefin polymerization, and process for production of olefin polymers with the same TOHO TITANIUM CO., LTD. (JP) 2014-02-11 US disclosed
US-20120053310-A1 Aminosilane Compounds, Catalyst Components and Catalysts for Olefin Polymerization, and Process for Production of Olefin Polymers with the Same TOHO TITANIUM CO., LTD. (JP) 2012-03-01 US disclosed
US-7141634-B2 Catalyst for olefin polymerization and process for polymerizing olefins TOHO CATALYST CO., LTD. (JP) 2006-11-28 US disclosed