Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786780 | 0.82 | HCRTR1 (0.87) | HCRTR1HCRTR2 | |
| SCHEMBL6376207 | 0.81 | HCRTR1 (0.86) | HCRTR1HCRTR2 | |
| SCHEMBL6375492 | 0.80 | HCRTR1 (0.87) | HCRTR1HCRTR2 | |
| SCHEMBL6787039 | 0.80 | HCRTR1 (0.87) | HCRTR1HCRTR2 | |
| SCHEMBL6374586 | 0.79 | HCRTR1 (0.72) | HCRTR1HCRTR2 | |
| SCHEMBL6790070 | 0.78 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL6789272 | 0.78 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL6376319 | 0.77 | HCRTR1 (0.72) | HCRTR1HCRTR2 | |
| SCHEMBL6382603 | 0.77 | HCRTR1 (0.88) | HCRTR1HCRTR2 | |
| SCHEMBL6375236 | 0.76 | HCRTR1 (0.67) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274687-A1 | 1,2,3,4- TETRAHYDROISOQUINOLINE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001068609-A1 | 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2001-09-20 | — | — | WO | disclosed |