Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | PLG | P00747 | 3/20 | 0.41 |
| ▸ | PROC | P04070 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7214326 | 0.99 | F10 (0.48) | F10F2PLGPROCPRSS1 | |
| Hydrochloric Acid SCHEMBL7214321 | 0.99 | F10 (0.48) | F10F2PLGPROCPRSS1 | |
| SCHEMBL7213626 | 0.91 | F10 (0.49) | F10F2PLGPROCPRSS1 | |
| Hydrochloric Acid SCHEMBL7219164 | 0.90 | F10 (0.49) | F10F2PLGPROCPRSS1 | |
| Hydrochloric Acid SCHEMBL7219163 | 0.90 | F10 (0.49) | F10F2PLGPROCPRSS1 | |
| SCHEMBL7921921 | 0.85 | F10 (0.39) | F10 | |
| SCHEMBL7214111 | 0.83 | F10 (0.50) | F10F2PLGPROCPRSS1 | |
| SCHEMBL7214115 | 0.82 | F10 (0.53) | F10F2PLGPROCPRSS1 | |
| SCHEMBL7213994 | 0.80 | F10 (0.48) | F10 | |
| Trifluoroacetic Acid SCHEMBL7214104 | 0.80 | F10 (0.44) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602864-B1 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| EP-0944386-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | disclosed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |
| WO-2001039759-A2 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |
| CN-1244798-A | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | RHONE POULENC RORER PHARMA (US) | 2000-02-16 | — | — | CN | disclosed |