Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219137 | 0.92 | F10 (0.40) | F10SIRT2 | |
| SCHEMBL7214111 | 0.87 | F10 (0.50) | F10SIRT2 | |
| SCHEMBL7921921 | 0.84 | F10 (0.39) | F10 | |
| SCHEMBL7219444 | 0.82 | F10 (0.38) | F10 | |
| Trifluoroacetic Acid SCHEMBL7214098 | 0.82 | F10 (0.45) | F10GRM2 | |
| SCHEMBL7213993 | 0.81 | F10 (0.50) | F10SIRT2 | |
| SCHEMBL7213622 | 0.80 | F10 (0.51) | F10 | |
| SCHEMBL7454004 | 0.79 | F10 (0.43) | F10 | |
| SCHEMBL7213556 | 0.79 | F10 (0.42) | F10 | |
| SCHEMBL7448512 | 0.79 | F10 (0.42) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | claimed |
| US-6602864-B1 | Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |