SCHEMBL7219456

SCHEMBL7219456

CCCCC(CC)COC(=O)C(C)CCC

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.62
TSHR P16473 3/20 0.62
TDP1 Q9NUW8 3/20 0.62
ATM Q13315 1/20 0.62
ALDH1A1 P00352 7/20 0.58
CA2 P00918 4/20 0.58
RECQL P46063 1/20 0.55
LMNA P02545 3/20 0.52
MAPK1 P28482 3/20 0.51
PRSS1 P07477 1/20 0.51
PRSS2 P07478 1/20 0.51
PRSS3 P35030 1/20 0.51
HSD17B10 Q99714 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.49
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP14 P50281 1/20 0.42
CA1 P00915 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7218980 0.95 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL21052460 0.95 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL7217028 0.91 CYP3A4 (0.60) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL1108109 0.91 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL18856352 0.91 CYP3A4 (0.49) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL7218092 0.90 PRSS1 (0.60) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL3809356 0.89 CYP3A4 (0.46) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL28610202 0.88 PRSS1 (0.61) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL27166015 0.88 CYP3A4 (0.60) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL7629758 0.88 CYP3A4 (0.60) CYP3A4TSHRTDP1ATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6667285-B1 Branched-chain carboxylic acid monoalkyl ester with outstanding hydrolytic stability NEW JAPAN CHEMICAL CO., LTD. (JP) 2003-12-23 US disclosed
EP-1225213-A1 LUBRICATING OIL FOR REFRIGERATOR, HYDRAULIC FLUID COMPOSITION FOR REFRIGERATOR AND METHOD FOR LUBRICATION OF REFRIGERATOR NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-07-24 EP disclosed
EP-0098791-B1 2-METHYLPENTANOIC-ACID ESTERS WITH BRANCHED OR CARBOCYCLIC ALCOHOLS, THEIR PREPARATION AND USE AS PERFUMING AGENTS Henkel Kommanditgesellschaft auf Aktien (DE) 1986-03-05 EP disclosed