Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 16/20 | 0.71 |
| ▸ | RARB | P10826 | 14/20 | 0.71 |
| ▸ | RARA | P10276 | 14/20 | 0.71 |
| ▸ | RXRA | P19793 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.71 |
| ▸ | GMNN | O75496 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | THPO | P40225 | 1/20 | 0.71 |
| ▸ | MTOR | P42345 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219676 | 1.00 | RARG (0.71) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL7219675 | 1.00 | RARG (0.71) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL9860852 | 0.92 | RARB (0.60) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL9860836 | 0.92 | RARB (0.60) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL9860689 | 0.92 | RARB (0.71) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL9860683 | 0.92 | RARB (0.71) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL10644468 | 0.91 | RARG (0.67) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL10644463 | 0.91 | RARG (0.67) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL10643544 | 0.89 | RARB (0.59) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL10643547 | 0.89 | RARB (0.59) | RARGRARBRARARXRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232779-B1 | VINYL PHENOL DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1988-10-12 | — | — | EP | claimed |
| US-4714786-A | Vinylphenol derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1987-12-22 | — | — | US | claimed |
| EP-0232779-A1 | Vinyl phenol derivatives, their preparation and their use | BASF Aktiengesellschaft (DE) | 1987-08-19 | — | — | EP | claimed |
| US-6627652-B1 | Treatment of diseases or conditions of the type which are normally treated with retinoid-like compounds is disclosed, with pharmaceutical compositions containing an active compound which is a selective agonist of the RXR retinoid | ALLERGAN, INC. | 2003-09-30 | — | — | US | disclosed |
| US-6624188-B1 | Administered to treat or prevent one or more of the diseases and conditions selected from the group consisting of dermatoses, atherosclerosis and restenosis resulting from neointimal hyperproliferation, non-malignant and | ALLERGAN, INC. | 2003-09-23 | — | — | US | disclosed |
| US-5475113-A | Treatment of skin disorders, skin cancer | ALLERGAN, INC. (US) | 1995-12-12 | — | — | US | disclosed |
| US-5455265-A | For mammals; skin disorders, cancer, inflammatory disease, cardiovascular diorders, autoimmune diseases and others | ALLERGAN, INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5055622-A | For treating neoplasms and dermatoses | HOFFMANN-LA ROCHE INC. (US) | 1991-10-08 | — | — | US | disclosed |
| US-5030765-A | Skin disorders, anititumor agents | HOFFMANN-LA ROCHE INC. (US) | 1991-07-09 | — | — | US | disclosed |
| US-5001276-A | Novel tetrahydronaphthalene and indane derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-03-19 | — | — | US | disclosed |
| US-4990703-A | Novel tetrahydronaphthalene and indane derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-02-05 | — | — | US | disclosed |
| US-4935560-A | ANTITUMOR AGENTS; SKIN DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4870219-A | NEOPLASMS, DERMATOSES | HOFFMANN-LA ROCHE INC. (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0232779-B1 | VINYL PHENOL DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1988-10-12 | — | — | EP | disclosed |
| US-4714786-A | Vinylphenol derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1987-12-22 | — | — | US | disclosed |
| EP-0232779-A1 | Vinyl phenol derivatives, their preparation and their use | BASF Aktiengesellschaft (DE) | 1987-08-19 | — | — | EP | disclosed |