Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6621233 | 0.84 | PARP14 (0.51) | BCHEPARP14CHRM2HTR1AADRA2A | |
| Fumaric Acid SCHEMBL7009266 | 0.84 | BCHE (0.50) | BCHEPARP14CHRM2HTR1AADRA2A | |
| Fumaric Acid SCHEMBL7227367 | 0.84 | BCHE (0.50) | BCHEPARP14CHRM2HTR1AADRA2A | |
| SCHEMBL6619355 | 0.84 | PARP14 (0.63) | BCHEPARP14CHRM2HTR1AADRA2A | |
| SCHEMBL7219755 | 0.78 | PARP14 (0.59) | BCHEPARP14CHRM2HTR1AADRA2A | |
| SCHEMBL7218894 | 0.78 | CHRM2 (0.49) | BCHEPARP14CHRM2HTR1AADRA2A | |
| SCHEMBL6619594 | 0.77 | PARP14 (0.61) | BCHEPARP14CHRM2HTR1AADRA2A | |
| SCHEMBL6621846 | 0.73 | PARP14 (0.48) | BCHEPARP14CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL6618531 | 0.72 | BCHE (0.51) | BCHEPARP14CHRM2HTR1AADRA2A | |
| SCHEMBL6621948 | 0.72 | PARP14 (0.58) | BCHEPARP14CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627630-B1 | Preventing or treating allergic skin diseases such as contact dermatitis, pruritus, dried dermatitis, acute urticaria prurigo and antiallergins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |