SCHEMBL721977

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL725506	0.86	KCNH2 (0.43)	KDRAURKBFGFR3FGFR2FGFR1
	SCHEMBL10268949	0.83	AURKB (0.46)	KDRMAP3K7TAB1AURKBFGFR3
	SCHEMBL721974	0.83	MAP3K7 (0.44)	KDRMAP3K7TAB1AURKBMET
	SCHEMBL721487	0.83	ADORA2A (0.45)	KDR
	SCHEMBL722228	0.82	PDE4C (0.43)	AURKBMETAURKAINCENPTPX2
	SCHEMBL724888	0.81	ACVR2A (0.48)	KDRMAP3K7TAB1AURKBAURKA
	SCHEMBL722397	0.81	AURKB (0.44)	KDRMAP3K7TAB1AURKBMET
	SCHEMBL721816	0.80	LRRK2 (0.45)	KCNH2GRM4FLT3METLRRK2
	SCHEMBL10267309	0.80	MKNK1 (0.43)	KDRAURKBFGFR3FGFR2FGFR1
	SCHEMBL722106	0.80	MTOR (0.47)	KDRMAP3K7TAB1AURKBMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.