Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TYMP | P19971 | 3/20 | 0.50 |
| ▸ | TK1 | P04183 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TK2 | O00142 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16382269 | 0.86 | MAPK1 (0.51) | MAPK1HPGDTYMPTK1TK2 | |
| SCHEMBL2641394 | 0.83 | MAPK1 (0.51) | MAPK1HPGDTYMPTK1TK2 | |
| SCHEMBL7213472 | 0.82 | UPP1 (0.47) | MAPK1TK1 | |
| SCHEMBL7215300 | 0.81 | MAPK1 (0.57) | MAPK1HPGDTYMPTK1ALDH1A1 | |
| SCHEMBL4088248 | 0.81 | UPP1 (0.57) | MAPK1HPGDTYMP | |
| SCHEMBL7215304 | 0.81 | TYMP (0.50) | MAPK1HPGDTYMPTK1TK2 | |
| SCHEMBL13402919 | 0.81 | TYMP (0.54) | MAPK1HPGDTYMPTK1TK2 | |
| SCHEMBL8444953 | 0.81 | TYMP (0.50) | MAPK1HPGDTYMPTK1ALDH1A1 | |
| SCHEMBL6029061 | 0.81 | HPGD (0.53) | MAPK1HPGDTYMPTK1TK2 | |
| SCHEMBL6029548 | 0.81 | TYMP (0.50) | MAPK1HPGDTYMPTK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37979-E1 | Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof | MITSUBISHI CHEMICAL CORPORATION | 2003-02-04 | — | — | US | disclosed |
| EP-0829476-B1 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | MITSUBISHI CHEM CORP (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-0829476-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5461060-A | Antiretroviral activity | MITSUBISHI KASEI CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |
| WO-1993002044-A1 | ACYCLIC 6-PHENYLSELENENYL PYRIMIDINE NUCLEOSIDES | BAKER CUMMINS PHARMACEUTICALS, INC. (US) | 1993-02-04 | — | — | WO | disclosed |
| EP-0420763-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1991-04-03 | — | — | EP | disclosed |