Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 8/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250918 | 0.87 | F10 (0.43) | HDAC3HDAC1F10KDM1AMAOB | |
| SCHEMBL7870016 | 0.82 | HDAC1 (0.58) | HDAC3HDAC1F10HDAC4HDAC7 | |
| SCHEMBL5758735 | 0.79 | F10 (0.46) | F10CYP2C9 | |
| SCHEMBL977627 | 0.78 | PTGER4 (0.47) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL30693377 | 0.78 | PTGER4 (0.47) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL3876083 | 0.77 | NSD2 (0.48) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL7406978 | 0.77 | HDAC3 (0.55) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL5224676 | 0.75 | HDAC3 (0.48) | HDAC3HDAC1F10 | |
| SCHEMBL20837293 | 0.75 | MAPT (0.53) | HDAC3HDAC1HDAC2CYP2D6CYP2C9 | |
| SCHEMBL5634334 | 0.75 | F10 (0.47) | HDAC3HDAC1F10KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610704-B1 | Inhibit factor Xa | ELI LILLY AND COMPANY | 2003-08-26 | — | — | US | disclosed |
| EP-1140881-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039111-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |