Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7220365

Cc1cc2ccncc2cc1CN1CC[C@H](N)C1=O.O=C(O)C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR6 P46095 8/20 0.40
PRMT3 O60678 1/20 0.36
F10 P00742 3/20 0.34
DPP4 P27487 3/20 0.34
DPP8 Q6V1X1 3/20 0.34
DPP9 Q86TI2 3/20 0.34
DPP7 Q9UHL4 3/20 0.34
HRH4 Q9H3N8 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
PDE9A O76083 1/20 0.34
F2 P00734 1/20 0.34
PLAT P00750 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7220364 0.89 GPR6 (0.39) GPR6PRMT3F10PDE9AF2
Trifluoroacetic Acid SCHEMBL7214110 0.88 GPR6 (0.38) GPR6PDE9A
Trifluoroacetic Acid SCHEMBL7219218 0.78 F10 (0.47) F10HRH4F2
Trifluoroacetic Acid SCHEMBL7219241 0.78 CYP2A6 (0.42) GPR6F10DPP4DPP8DPP9
Trifluoroacetic Acid SCHEMBL7214109 0.77 GPR6 (0.37) GPR6F10
Trifluoroacetic Acid SCHEMBL6222163 0.74 F10 (0.49) F10DPP4DPP7HRH4HRH3
Trifluoroacetic Acid SCHEMBL7453374 0.74 F10 (0.49) F10DPP4DPP7HRH4HRH3
Trifluoroacetic Acid SCHEMBL7220305 0.74 GPR6 (0.35) GPR6HRH3
Trifluoroacetic Acid SCHEMBL7377917 0.73 DPP4 (0.39) GPR6DPP4DPP8DPP9DPP7
Trifluoroacetic Acid SCHEMBL7214395 0.72 F10 (0.43) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6602864-B1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-08-05 US claimed