Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908559 | 0.91 | MAP3K11 (1.00) | MAP3K11LRRK2 | |
| SCHEMBL722934 | 0.87 | MAP3K11 (1.00) | MAP3K11LRRK2 | |
| SCHEMBL7899779 | 0.87 | MAP3K11 (1.00) | MAP3K11LRRK2 | |
| SCHEMBL722624 | 0.84 | MAP3K11 (1.00) | MAP3K11LRRK2 | |
| SCHEMBL721886 | 0.84 | MAP3K11 (0.75) | MAP3K11LRRK2 | |
| SCHEMBL720512 | 0.83 | MAP3K11 (1.00) | MAP3K11LRRK2 | |
| SCHEMBL723157 | 0.83 | MAP3K11 (1.00) | MAP3K11LRRK2 | |
| SCHEMBL722945 | 0.83 | MAP3K11 (1.00) | MAP3K11LRRK2 | |
| SCHEMBL721930 | 0.83 | MAP3K11 (0.86) | MAP3K11LRRK2 | |
| SCHEMBL720528 | 0.82 | MAP3K11 (1.00) | MAP3K11LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877772-B2 | Substituted pyrrolo[2,3-B]pyridines as MLK inhibitors | UNIVERSITY OF ROCHESTER (US) | 2014-11-04 | — | — | US | disclosed |
| US-20120053175-A1 | MLK INHIBITORS AND METHODS OF USE | UNIVERSITY OF ROCHESTER (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053175-A1 | MLK INHIBITORS AND METHODS OF USE | MAP3K20, MAP3K2, MAP3K7 | MAP3K11 23/4885LRRK2 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.