Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.69 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.69 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279448 | 0.85 | AKR1B1 (0.55) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL29463586 | 0.84 | KDM4E (0.65) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Chromocarb SCHEMBL29355904 | 0.82 | KDM4E (1.00) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Chromocarb SCHEMBL432304 | 0.82 | KDM4E (1.00) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Chromocarb SCHEMBL29695542 | 0.80 | KDM4E (0.96) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Chromocarb SCHEMBL6633182 | 0.80 | KDM4E (0.96) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Chromocarb SCHEMBL27958709 | 0.80 | KDM4E (0.96) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Chromocarb SCHEMBL28113935 | 0.80 | KDM4E (0.96) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Flavone SCHEMBL5394276 | 0.79 | KDM4E (0.79) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL5275063 | 0.79 | AKR1B1 (1.00) | KDM4EUSP2CSNK2A2PTGS1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552054-B1 | For prophylaxis and therapy of bone diseases and chondropathy | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-1211251-A1 | CHROMONE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-06-05 | — | — | EP | disclosed |