⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220874 | 0.74 | — | — | |
| SCHEMBL24325670 | 0.74 | — | — | |
| SCHEMBL7220875 | 0.74 | — | — | |
| SCHEMBL26752689 | 0.74 | — | — | |
| SCHEMBL17988358 | 0.65 | MAPT (0.39) | — | |
| SCHEMBL7349983 | 0.62 | — | — | |
| SCHEMBL7349985 | 0.62 | — | — | |
| SCHEMBL10920917 | 0.62 | — | — | |
| SCHEMBL2161647 | 0.62 | HTT (0.48) | — | |
| SCHEMBL2161643 | 0.62 | HTT (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6503898-B1 | Administering 4,7-dibenzyl-5,6-dihydroxy-N,N*-di(m-aminobenzyl)--1,3-diazepin-2-one or salt to treat human immunodeficiency virus infection | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-01-07 | — | — | US | disclosed |
| CN-1029964-C | Novel N-(4-piperidinyl) Bicyclic condensed 2-imidazolamine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1995-10-11 | — | — | CN | disclosed |
| EP-0295742-B1 | NOVEL N-(4-PIPERIDINYL) BICYCLIC CONDENSED 2-IMIDAZOLAMINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-08-26 | — | — | EP | disclosed |
| US-4897401-A | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases | JANSSEN PHARMACEUTICAL N.V. (BE) | 1990-01-30 | — | — | US | disclosed |
| CN-88103784-A | N- (4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives | — | 1988-12-28 | — | — | CN | disclosed |
| EP-0295742-A1 | Novel N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-12-21 | — | — | EP | disclosed |