Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 9/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773647 | 0.92 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL7222196 | 0.91 | MAPK14 (0.52) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5770554 | 0.86 | MAPK14 (0.59) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5770578 | 0.84 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769853 | 0.84 | MAPK14 (0.52) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769817 | 0.84 | MAPK14 (0.57) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5768059 | 0.84 | MAPK14 (0.53) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769100 | 0.84 | MAPK14 (0.58) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL7222181 | 0.83 | MAPK13 (0.48) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769147 | 0.83 | MAPK14 (0.54) | MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |