Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 10/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772516 | 0.84 | MAPK13 (0.42) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL5771075 | 0.83 | MAPK13 (0.42) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL7221066 | 0.81 | MAPK13 (0.40) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL5771151 | 0.81 | MAPK13 (0.46) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5770947 | 0.80 | MAPK13 (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5771178 | 0.79 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL5770752 | 0.78 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL5772001 | 0.78 | MAPK14 (0.50) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL5772757 | 0.78 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5766940 | 0.77 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |