Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221129 | 0.92 | KDM4E (0.53) | HRH3KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7221123 | 0.80 | HRH3 (0.39) | HRH3KMT2AMEN1HTR7 | |
| SCHEMBL7223610 | 0.79 | GCGR (0.54) | HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7221053 | 0.79 | GCGR (0.54) | HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7230397 | 0.78 | GCGR (0.53) | HRH3ALDH1A1 | |
| SCHEMBL7223611 | 0.77 | DRD4 (0.41) | KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7223077 | 0.77 | SLC6A2 (0.40) | KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7229131 | 0.76 | SMN1; SMN2 (0.46) | HRH3KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7221489 | 0.76 | SMN1; SMN2 (0.48) | HRH3KDM4EALDH1A1HTR7 | |
| SCHEMBL7221491 | 0.76 | DRD4 (0.38) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | disclosed |